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Rho-Related GTP-Binding Protein RhoB (ARHB) Antibody
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Catalogue No: abx026689
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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ARHB mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Research Articles on Rho-Related GTP-Binding Protein RhoB (ARHB)
| Target | Rho-Related GTP-Binding Protein RhoB (ARHB) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/4000, IHC-P: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 104-137 amino acids from the Central region of human ARHB. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P62745 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R692, P01121, Q5U0H6, Q7RTN5, Q7RTR9, Q9CUV7 |
| UniProt Entry Name | RHOB_HUMAN |
| KEGG | hsa:388 |
| String | 9606.ENSP00000272233 |
| Molecular Weight | Calculated MW: 22.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat and Cow RHOB. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |