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Introduction | Bcl2 Associated X Protein (BAX) is a protein that plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM). |
Target | Bcl2 Associated X Protein (BAX) |
Reactivity | Human, Mouse, Rat |
Tested Applications | ELISA |
Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Validity | 6 months. |
UniProt Primary AC | Q07812 (UniProt, ExPASy) |
Gene Symbol | BAX |
GeneID | 581 |
OMIM | 600040 |
HGNC | 959 |
Ensembl | ENSG00000087088 |
Detection Method | Colorimetric |
Plate Coating | Uncoated |
Substrate | TMB |
Detection Antibody Conjugation | HRP |
Availability | Shipped within 1-2 weeks. |
Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |