B-Cell Lymphoma/Leukaemia 11A (BCL11A) Antibody

BCL11A Antibody is a Rabbit Polyclonal antibody against BCL11A. This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.

Target	B-Cell Lymphoma/Leukaemia 11A (BCL11A)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CTIP1/CTIP1/BCL11A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9H165 (UniProt, ExPASy)
UniProt Entry Name	BC11A_HUMAN
Gene Symbol	BCL11A
GeneID	53335
NCBI Accession	NP_060484.2
String	9606.ENSP00000338774
Molecular Weight	Calculated MW: 91 kDa Observed MW: 113 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on B-Cell Lymphoma/Leukaemia 11A (BCL11A)

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