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CD27 Antigen / TNFRSF7 (CD27) Antibody
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Catalogue No: abx027573
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor.
Research Articles on CD27 Antigen / TNFRSF7 (CD27)
| Target | CD27 Antigen / TNFRSF7 (CD27) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 196-225 amino acids from the C-terminal region of human CD27. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P26842 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RDZ0 |
| Gene Symbol | CD27 |
| KEGG | hsa:939 |
| String | 9606.ENSP00000266557 |
| Molecular Weight | Calculated MW: 29.1 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |