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Keratin, Type II Cytoskeletal 8 (KRT8) Antibody
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Catalogue No: abx010621
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
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Cytokeratin 8, also known as CK8, KRT8, K8. Entrez Protein NP002264. It is a member of the type II keratin family.Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.It typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Research Articles on Keratin, Type II Cytoskeletal 8 (KRT8)
| Target | Keratin, Type II Cytoskeletal 8 (KRT8) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human Cytokeratin (aa391-483) expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P05787 (UniProt, ExPASy) |
| UniProt Entry Name | K2C8_HUMAN |
| Gene Symbol | KRT8 |
| GeneID | 3856 |
| OMIM | 148060 |
| HGNC | 6446 |
| KEGG | hsa:3856 |
| Ensembl | ENSG00000170421 |
| String | 9606.ENSP00000449404 |
| Molecular Weight | 54 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |