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Dynamin-1 (DNM1) Antibody

Catalogue No: abx002132
Price: £120.00
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Dynamin-1 (DNM1) Antibody

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DNM1 Antibody is a Rabbit Polyclonal antibody against DNM1. This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.

Target DNM1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human DNM1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q05193 (UniProt, ExPASy)
UniProt Secondary AC A6NLM6, Q5SYX0, Q5SYX2, Q6P3T6, Q86VD2
UniProt Entry Name DYN1_HUMAN
Gene Symbol DNM1
GeneID 1759
KEGG hsa:1759
String 9606.ENSP00000362014
Molecular Weight Calculated MW: 95 kDa, 96 kDa, 97 kDa
Observed MW: 117 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Dynamin-1 (DNM1) Antibody

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