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Dynamin-1-Like Protein (DRP1) Antibody
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Catalogue No: abx010669
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
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Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.
Research Articles on Dynamin-1-Like Protein (DRP1)
| Target | Dynamin-1-Like Protein (DRP1) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human Dynamin-1 expressed in E. coli. |
| Isotype | IgG2a |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q05193 (UniProt, ExPASy) |
| UniProt Secondary AC | A6NLM6, Q5SYX0, Q5SYX2, Q6P3T6, Q86VD2 |
| UniProt Entry Name | DYN1_HUMAN |
| Gene Symbol | DNM1 |
| GeneID | 1759 |
| OMIM | 602377 |
| HGNC | 2972 |
| KEGG | hsa:1759 |
| Ensembl | ENSG00000106976 |
| String | 9606.ENSP00000362014 |
| Molecular Weight | 97 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |