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Ephrin Type-B Receptor 6 (EphB6) Antibody
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Catalogue No: abx033539
Price:
US$326.25
(Size: 80 µl)
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Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB6 lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.
Research Articles on Ephrin Type-B Receptor 6 (EphB6)
| Target | Ephrin Type-B Receptor 6 (EphB6) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 990-1021 amino acids from the C-terminal region of human EphB6. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15197 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D2I7, A8CDT5, D3DXD3, Q2TB23, Q2TB24 |
| UniProt Entry Name | EPHB6_HUMAN |
| Gene Symbol | EPHB6 |
| NCBI Accession | NP_001267723.1 NP_001267724.1 NP_004436.3 |
| KEGG | hsa:2051 |
| String | 9606.ENSP00000481994 |
| Molecular Weight | Calculated MW: 111 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |