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Glutamate Receptor, Metabotropic 3 (GRM3) Antibody

Catalogue No: abx001976
Price: £120.00
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Glutamate Receptor, Metabotropic 3 (GRM3) Antibody

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GRM3 Antibody is a Rabbit Polyclonal antibody against GRM3. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Target GRM3
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GRM3.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14832 (UniProt, ExPASy)
UniProt Secondary AC Q2PNZ6, Q75MV4, Q75N17, Q86YG6, Q8TBH9
UniProt Entry Name GRM3_HUMAN
Gene Symbol GRM3
GeneID 2913
KEGG hsa:2913
String 9606.ENSP00000355316
Molecular Weight Calculated MW: 60 kDa, 98 kDa
Observed MW: 112 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glutamate Receptor, Metabotropic 3 (GRM3) Antibody

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