Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB) Antibody

HADHB encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Target	Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 315-342 amino acids from the C-terminal region of human HADHB.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P55084 (UniProt, ExPASy)
UniProt Secondary AC	B2RB16, B4E2W0, O14969, Q53TA6, Q96C77, Q9H3F5, Q9T2V8
UniProt Entry Name	ECHB_HUMAN
KEGG	hsa:3032
String	9606.ENSP00000325136
Molecular Weight	Calculated MW: 51.3 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Cow and Monkey HADHB.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Trifunctional Enzyme Subunit Beta, Mitochondrial (HADHB)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue