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Human Promyelocytic Leukemia Protein (PML) Protein
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Catalogue No: abx068694
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US$232.00
(Size: 10 µg)
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Human Promyelocytic Leukemia Protein (PML) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli). This protein is the immunogen for the following antibodies: abx103063
Research Articles on Promyelocytic Leukemia Protein (PML)
| Target | Promyelocytic Leukemia Protein (PML) |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | WB, SDS-PAGE |
| Host | E. coli |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Activity | Not tested |
| Purity | > 97% |
| Reconstitution | Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P29590 (UniProt, ExPASy) |
| UniProt Entry Name | PML_HUMAN |
| Gene Symbol | PML |
| GeneID | 5371 |
| OMIM | 102578 |
| HGNC | 9113 |
| KEGG | hsa:5371 |
| Ensembl | ENSG00000140464 |
| String | 9606.ENSP00000268058 |
| Molecular Weight | Calculated MW: 27.2 kDa Observed MW (SDS-PAGE): 31 kDa Possible reasons why the actual band size differs from the predicted band size: 1. Splice variants. Alternative splicing may create different sized proteins from the same gene. 2. Relative charge. The composition of amino acids may affect the charge of the protein. 3. Post-translational modification. Phosphorylation, glycoslyation, methylation etc. may affect the band size. 4. Post-translational cleavage. Many proteins are synthesised as pro-proteins, and then cleaved to give the active form. 5. Polymerisation of the target protein. Dimerisation, multimerisation etc. will increase the band size observed. |
| Sequence Fragment | Gln59-Glu239 |
| Sequence | QC QAEAKCPKLL PCLHTLCSGC LEASGMQCPI CQAPWPLGAD TPALDNVFFE SLQRRLSVYR QIVDAQAVCT RCKESADFWC FECEQLLCAK CFEAHQWFLK HEARPLAELR NQSVREFLDG TRKTNNIFCS NPNHRTPTLT SIYCRGCSKP LCCSCALLDS SHSELKCDIS AEIQQRQEE |
| Tag | N-terminal His tag |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Concentration | Prior to lyophilization: 100 µg/ml |
| Availability | Shipped within 5-7 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |