Interferon Regulatory Factor 3 (IRF3) Antibody

Interferon Regulatory Factor 3 (IRF3) Antibody is a Rabbit Polyclonal antibody for the detection of IRF3.

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Target	Interferon Regulatory Factor 3 (IRF3)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	ELISA, WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	interferon regulatory factor 3
Isotype	IgG
Form	Liquid
Purity	≥ 95% (SDS-PAGE)
Purification	Purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Validity	12 months.
UniProt Primary AC	Q14653 (UniProt, ExPASy)
UniProt Secondary AC	A8K7L2, B2RAZ3, Q5FBY1, Q5FBY2, Q5FBY4, Q7Z5G6
UniProt Entry Name	IRF3_HUMAN
Gene Symbol	IRF3
GeneID	3661
OMIM	603734
HGNC	6118
KEGG	hsa:3661
Ensembl	ENSG00000126456
String	9606.ENSP00000471896
Molecular Weight	Observed MW: 50-55 kDa
Buffer	PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.
Concentration	2 mg/ml
Availability	Shipped within 5-12 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Interferon Regulatory Factor 3 (IRF3)

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