Interferon Regulatory Factor 8 (IRF8) Antibody

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Catalogue No: abx004441
Price: US$217.50
(Size: 20 µl)

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Western blot analysis of lysates from HL-60 cells, using IRF8 Antibody at 1/400 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Exposure time: 180s.
Interferon Regulatory Factor 8 (IRF8) Antibody

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Datasheet SDS
IRF8 Antibody is a Rabbit Polyclonal antibody against IRF8. Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Target Interferon Regulatory Factor 8 (IRF8)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 137-426 of human IRF8.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q02556 (UniProt, ExPASy)
UniProt Secondary AC A0AV82
UniProt Entry Name IRF8_HUMAN
Gene Symbol IRF8
GeneID 3394
NCBI Accession NP_002154.1
KEGG hsa:3394
String 9606.ENSP00000268638
Molecular Weight Calculated MW: 48 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Interferon Regulatory Factor 8 (IRF8)


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