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KDR / FLK1 (pY996) Antibody
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Catalogue No: abx031863
Price:
US$326.25
(Size: 80 µl)
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KDR (FLK1) is a receptor for VEGF or VEGFC. This protein has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
Research Articles on KDR/FLK1 (pY996)
| Target | KDR/FLK1 (pY996) |
| Clonality | Polyclonal |
| Target Modification | Tyr996 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y996 of human KDR/FLK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P35968 (UniProt, ExPASy) |
| UniProt Secondary AC | A2RRS0, B5A925, C5IFA0, O60723, Q14178 |
| UniProt Entry Name | VGFR2_HUMAN |
| NCBI Accession | NP_002244.1 |
| KEGG | hsa:3791 |
| String | 9606.ENSP00000263923 |
| Molecular Weight | Calculated MW: 152 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |