+44 (0) 1223 755950
+1 832 327 7413
Mitogen Activated Protein Kinase Kinase Kinase 12 (MAP3K12) Antibody
REQUEST MORE INFO
Catalogue No: abx025426
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
This gene encodes a member of the serine/threonine protein kinase family. This kinase contains a leucine-zipper domain and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation. Alternatively spliced transcript variants encoding different proteins have been described.[provided by RefSeq].
Research Articles on Mitogen Activated Protein Kinase Kinase Kinase 12 (MAP3K12)
| Target | Mitogen Activated Protein Kinase Kinase Kinase 12 (MAP3K12) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Mouse |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 828-859 amino acids from human MAP3K12. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified Mouse Monoclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q12852 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KSS9, G3V1Y2, Q86VQ5, Q8WY25 |
| UniProt Entry Name | M3K12_HUMAN |
| KEGG | hsa:7786 |
| String | 9606.ENSP00000448689 |
| Molecular Weight | Calculated MW: 93.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |