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Megakaryocyte Associated Tyrosine Kinase (MATK) Antibody
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Catalogue No: abx011115
Price:
US$427.75
(Size: 100 µl)
Orders to United States ship from United States
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MATK (megakaryocyte-associated tyrosine kinase), also known as CTK, this protein has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer.
Research Articles on Megakaryocyte Associated Tyrosine Kinase (MATK)
| Target | Megakaryocyte Associated Tyrosine Kinase (MATK) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, FCM |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of human MATK expressed in E. coli. |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P42679 (UniProt, ExPASy) |
| UniProt Secondary AC | B3KNZ9, Q9NST8 |
| UniProt Entry Name | MATK_HUMAN |
| Gene Symbol | MATK |
| GeneID | 4145 |
| OMIM | 600038 |
| HGNC | 6906 |
| KEGG | hsa:4145 |
| Ensembl | ENSG00000007264 |
| String | 9606.ENSP00000378485 |
| Molecular Weight | 56 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |