+44 (0) 1223 755950
+1 832 327 7413
G/T Mismatch-Binding Protein (MSH6) Antibody
REQUEST MORE INFO
Catalogue No: abx000936
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
Reviews: 
(0 Publications and Reviews)
(0 Publications and Reviews)
Click on the image to see the image legend
MSH6 Antibody is a Rabbit Polyclonal antibody against MSH6. This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
Research Articles on G/T Mismatch-Binding Protein (MSH6)
| Target | G/T Mismatch-Binding Protein (MSH6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat, Monkey |
| Tested Applications | WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human MSH6 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P52701 (UniProt, ExPASy) |
| UniProt Secondary AC | B4DF41, B4E3I4, F5H2F9, O43706, O43917, Q8TCX4, Q9BTB5 |
| UniProt Entry Name | MSH6_HUMAN |
| Gene Symbol | MSH6 |
| GeneID | 2956 |
| NCBI Accession | NP_000170.1 |
| KEGG | hsa:2956 |
| String | 9606.ENSP00000234420 |
| Molecular Weight | Calculated MW: 119 kDa/120 kDa/137 kDa/152 kDa |
| Buffer | PBS, pH 7.3, containing 0.01% thiomersal, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
