Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody

MyD88 Antibody is a Rabbit Polyclonal antibody against MyD88. This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Target	Myeloid Differentiation Primary Response Protein MyD88 (MYD88)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 20-140 of human MyD88.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q99836 (UniProt, ExPASy)
UniProt Entry Name	MYD88_HUMAN
Gene Symbol	MYD88
GeneID	4615
NCBI Accession	NP_002459.2
KEGG	hsa:4615
String	9606.ENSP00000401399
Molecular Weight	Calculated MW: 33 kDa Observed MW: 33 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Myeloid Differentiation Primary Response Protein MyD88 (MYD88)

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