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Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody

Catalogue No: abx000933
Price: £120.00
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Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody

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MyD88 Antibody is a Rabbit Polyclonal antibody against MyD88. This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Target Myeloid Differentiation Primary Response Protein MyD88 (MYD88)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human MyD88.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q99836 (UniProt, ExPASy)
UniProt Entry Name MYD88_HUMAN
Gene Symbol MYD88
GeneID 4615
KEGG hsa:4615
String 9606.ENSP00000401399
Molecular Weight Calculated MW: 15 kDa, 20 kDa, 28 kDa, 31 kDa, 33 kDa, 34 kDa
Observed MW: 35 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Myeloid Differentiation Primary Response Protein MyD88 (MYD88) Antibody

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