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Oxoglutarate Dehydrogenase (OGDH) Antibody
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Catalogue No: abx004886
Price:
US$217.50
(Size: 20 µl)
Orders to United States ship from United States
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OGDH Antibody is a Rabbit Polyclonal antibody against OGDH. This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Research Articles on Oxoglutarate Dehydrogenase (OGDH)
| Target | Oxoglutarate Dehydrogenase (OGDH) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/10 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human OGDH. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02218 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E2U9, D3DVL0, E9PBM1, Q96DD3, Q9UDX0 |
| UniProt Entry Name | ODO1_HUMAN |
| Gene Symbol | OGDH |
| GeneID | 4967 |
| NCBI Accession | NP_001003941.1 |
| KEGG | hsa:4967 |
| String | 9606.ENSP00000222673 |
| Molecular Weight | Calculated MW: 116 kDa Observed MW: 110 kDa |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |