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Presenilin Associated Rhomboid Like (PARL) Antibody
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Catalogue No: abx011320
Price:
US$427.75
(Size: 100 µl)
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PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Research Articles on Presenilin Associated Rhomboid Like (PARL)
| Target | Presenilin Associated Rhomboid Like (PARL) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA |
| Host | Mouse |
| Recommended dilutions | ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Purified recombinant fragment of PARL (aa112-167) expressed in E. coli. |
| Isotype | IgG2b |
| Form | Liquid |
| Purification | Unpurified ascites. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9H300 (UniProt, ExPASy) |
| UniProt Secondary AC | Q96CQ4, Q9BTJ6, Q9P1E3 |
| UniProt Entry Name | PARL_HUMAN |
| Gene Symbol | PARL |
| GeneID | 55486 |
| OMIM | 607858 |
| HGNC | 18253 |
| Ensembl | ENSG00000175193 |
| String | 9606.ENSP00000325421 |
| Molecular Weight | 42 kDa |
| Buffer | Ascitic fluid containing 0.03% sodium azide. |
| Concentration | Not determined. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |