Presenilin Associated Rhomboid Like (PARL) Antibody

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Catalogue No: abx011320
Price: US$427.75
(Size: 100 µl)

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Western blot analysis using PARL antibody against truncated Trx-PARL recombinant protein (1) and truncated MBP-PARL (aa112-167) recombinant protein (2).
Presenilin Associated Rhomboid Like (PARL) Antibody

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Datasheet SDS
PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

Target Presenilin Associated Rhomboid Like (PARL)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA
Host Mouse
Recommended dilutions ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of PARL (aa112-167) expressed in E. coli.
Isotype IgG2b
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Shelf Life 12 months.
UniProt Primary AC Q9H300 (UniProt, ExPASy)
UniProt Secondary AC Q96CQ4, Q9BTJ6, Q9P1E3
UniProt Entry Name PARL_HUMAN
Gene Symbol PARL
GeneID 55486
OMIM 607858
HGNC 18253
Ensembl ENSG00000175193
String 9606.ENSP00000325421
Molecular Weight 42 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Presenilin Associated Rhomboid Like (PARL)


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