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Platelet Derived Growth Factor Receptor Alpha (PDGFRA) Antibody
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Catalogue No: abx001715
Price:
US$217.50
(Size: 20 µl)
Orders to United States ship from United States
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PDGFRA Antibody is a Rabbit Polyclonal antibody against PDGFRA. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.
Research Articles on Platelet Derived Growth Factor Receptor Alpha (PDGFRA)
| Target | Platelet Derived Growth Factor Receptor Alpha (PDGFRA) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 896-1059 of human PDGFR alpha. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16234 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RE69, E9PBH0, Q6P4H5, Q96KZ7, Q9UD28 |
| Gene Symbol | PDGFRA |
| GeneID | 5156 |
| NCBI Accession | NP_006197.1 |
| Molecular Weight | Calculated MW: 123 kDa Observed MW: 150-190 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |