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PIK3CG (pS1100) Antibody
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Catalogue No: abx031996
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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PIK3CG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
Research Articles on PIK3CG (pS1100)
| Target | PIK3CG (pS1100) |
| Clonality | Polyclonal |
| Target Modification | Ser1100 |
| Modification | Phosphorylation |
| Reactivity | Human |
| Tested Applications | ELISA, DB |
| Host | Rabbit |
| Recommended dilutions | DB: 1/500. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1100 of human PIK3CG. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified in a 2-step procedure with the control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48736 (UniProt, ExPASy) |
| UniProt Secondary AC | A4D0Q6, Q8IV23, Q9BZC8 |
| UniProt Entry Name | PK3CG_HUMAN |
| KEGG | hsa:5294 |
| String | 9606.ENSP00000352121 |
| Molecular Weight | Calculated MW: 126 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Pig PIK3CG. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |