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Polymerase DNA Directed Beta (POLB) Antibody
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Catalogue No: abx001412
Price:
US$232.00
(Size: 20 µl)
Orders to United States ship from United States
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![Western blot analysis of various lysates using [KO Validated] DNA Polymerase beta Antibody at 1/1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) at 1/10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST.](https://www.abbexa.com/image/cache/data/products/18B/abx001412_1-500x500.jpg "Polymerase DNA Directed Beta (POLB) Antibody")
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POLB Antibody is a Rabbit Polyclonal antibody against POLB. The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011].
Research Articles on Polymerase DNA Directed Beta (POLB)
| Target | Polymerase DNA Directed Beta (POLB) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/200 - 1/1000, IHC-P: 1/50 - 1/200, IF/ICC: 1/20 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human DNA Polymerase beta. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P06746 (UniProt, ExPASy) |
| UniProt Secondary AC | B2RC78, Q3KP48, Q6FI34 |
| UniProt Entry Name | DPOLB_HUMAN |
| Gene Symbol | POLB |
| GeneID | 5423 |
| NCBI Accession | NP_002681.1 |
| KEGG | hsa:5423 |
| String | 9606.ENSP00000265421 |
| Molecular Weight | Calculated MW: 38 kDa Observed MW: 37 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |