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Leucine Rich Repeat Protein 1 / PPIL5 (LRR1) Antibody
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Catalogue No: abx030021
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.
Research Articles on Leucine Rich Repeat Protein 1 / PPIL5 (LRR1)
| Target | Leucine Rich Repeat Protein 1 / PPIL5 (LRR1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 127-153 amino acids from the Central region of human PPIL5. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q96L50 (UniProt, ExPASy) |
| UniProt Secondary AC | A5D6X3, B4DDE0, Q52M24, Q86SZ1, Q8N6H9 |
| UniProt Entry Name | LLR1_HUMAN |
| Gene Symbol | LRR1 |
| KEGG | hsa:122769 |
| String | 9606.ENSP00000298288 |
| Molecular Weight | Calculated MW: 46.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |