Leucine Rich Repeat Protein 1 / PPIL5 (LRR1) Antibody

The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Target	Leucine Rich Repeat Protein 1 / PPIL5 (LRR1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 127-153 amino acids from the Central region of human PPIL5.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q96L50 (UniProt, ExPASy)
UniProt Secondary AC	A5D6X3, B4DDE0, Q52M24, Q86SZ1, Q8N6H9
UniProt Entry Name	LLR1_HUMAN
Gene Symbol	LRR1
KEGG	hsa:122769
String	9606.ENSP00000298288
Molecular Weight	Calculated MW: 46.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Leucine Rich Repeat Protein 1 / PPIL5 (LRR1)

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