Protein Phosphatase 2 Scaffold Subunit Abeta (PPP2R1B) Antibody

PPP2R1B Antibody is a Rabbit Polyclonal antibody against PPP2R1B. This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.

Target	Protein Phosphatase 2 Scaffold Subunit Abeta (PPP2R1B)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 468-667 of human PP2A-Abeta/PR65β/PP2A-Aβ/PR65β/PPP2R1B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P30154 (UniProt, ExPASy)
UniProt Entry Name	2AAB_HUMAN
Gene Symbol	PPP2R1B
GeneID	5519
NCBI Accession	NP_859050.1
KEGG	hsa:5519
String	9606.ENSP00000311344
Molecular Weight	Calculated MW: 66 kDa Observed MW: 65 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	3.33 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Phosphatase 2 Scaffold Subunit Abeta (PPP2R1B)

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