Protein Phosphatase 3 Catalytic Subunit Alpha (PPP3CA) Antibody

PPP3CA Antibody is a Rabbit Polyclonal antibody against PPP3CA. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-Aå, PP2B-A∫ and PP2B-A©. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.

Target	Protein Phosphatase 3 Catalytic Subunit Alpha (PPP3CA)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-511 of human Calcineurin A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q08209 (UniProt, ExPASy)
UniProt Secondary AC	A1A441, A8K3B7, A8W6Z7, A8W6Z8, B5BUA2, Q8TAW9
Gene Symbol	PPP3CA
GeneID	5530
NCBI Accession	NP_001124163.1
Molecular Weight	Calculated MW: 59 kDa Observed MW: 57 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Protein Phosphatase 3 Catalytic Subunit Alpha (PPP3CA)

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