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Poly(U) Binding Splicing Factor 60 (PUF60) Antibody
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Catalogue No: abx028005
Price:
US$326.25
(Size: 80 µl)
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The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Research Articles on Poly(U) Binding Splicing Factor 60 (PUF60)
| Target | Poly(U) Binding Splicing Factor 60 (PUF60) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human PUF60. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q9UHX1 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K8K8, Q969E7, Q96D94, Q96H63, Q99628, Q9NZA0, Q9UJY7 |
| UniProt Entry Name | PUF60_HUMAN |
| Gene Symbol | PUF60 |
| String | 9606.ENSP00000434359 |
| Molecular Weight | Calculated MW: 59.9 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |