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Dual Specificity Protein Phosphatase 6 (DUSP6) Antibody
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Catalogue No: abx033957
Price:
US$326.25
(Size: 80 µl)
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Dual Specificity Protein Phosphatase 6 (DUSP6) Antibody is a Rabbit Polyclonal antibody for the detection of DUSP6. Dual specificity protein tyrosine phosphatases (dsPTPs) are a subfamily of protein tyrosine phosphatases implicated in the regulation of mitogen-activated protein kinase (MAPK). MKP-1 (also known as CL100, 3CH134, Erp, and hVH-1) exemplifies a class of dual-specificity phosphatase able to reverse the activation of MAP kinases by dephosphorylating critical tyrosine and threonine residues. MKP-3 is 36% identical to MKP-1 and it blocks both the phosphorylation and enzymatic activation of ERK2 by mitogens. MKP-3 mRNA is expressed in lung, heart, brain, and kidney, but not significantly in skeletal muscle or testis.
Research Articles on Dual Specificity Protein Phosphatase 6 (DUSP6)
| Target | Dual Specificity Protein Phosphatase 6 (DUSP6) |
| Clonality | Polyclonal |
| Reactivity | Rat |
| Tested Applications | ELISA, WB, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | 6x HIS-tagged recombinant protein encoding 1-381 AA of rat MKP3. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q64346 (UniProt, ExPASy) |
| UniProt Entry Name | DUS6_RAT |
| NCBI Accession | NP_446335.1 |
| KEGG | rno:116663 |
| String | 10116.ENSRNOP00000032969 |
| Molecular Weight | Calculated MW: 42.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |