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Ribosomal Protein S6 (RPS6) Antibody
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Catalogue No: abx004661
Price:
US$348.00
(Size: 60 µl)
Orders to United States ship from United States
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RPS6 Antibody is a Rabbit Monoclonal antibody against RPS6. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Research Articles on Ribosomal Protein S6 (RPS6)
| Target | Ribosomal Protein S6 (RPS6) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | A synthetic peptide corresponding to human RPS6 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P62753 (UniProt, ExPASy) |
| UniProt Secondary AC | P08227, P10660, Q4VBY7, Q8N6Z7 |
| UniProt Entry Name | RS6_HUMAN |
| Gene Symbol | RPS6 |
| GeneID | 6194 |
| OMIM | 180460 |
| NCBI Accession | NP_001001.2 |
| HGNC | 10429 |
| KEGG | hsa:6194 |
| Ensembl | ENSG00000137154 |
| String | 9606.ENSP00000369757 |
| Molecular Weight | Calculated MW: 28 kDa Observed MW: 28 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
