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Histone Deacetylase Complex Subunit SAP18 (SAP18) Antibody
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Catalogue No: abx003279
Price:
US$217.50
(Size: 20 µl)
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SAP18 Antibody is a Rabbit Polyclonal antibody against SAP18. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
Research Articles on Histone Deacetylase Complex Subunit SAP18 (SAP18)
| Target | Histone Deacetylase Complex Subunit SAP18 (SAP18) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/200 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 21-172 of human SAP18. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O00422 (UniProt, ExPASy) |
| UniProt Secondary AC | B2R494, Q2TTR4, Q6IAW9, Q8N606, Q9UF14, X6RAL5 |
| UniProt Entry Name | SAP18_HUMAN |
| Gene Symbol | SAP18 |
| GeneID | 10284 |
| NCBI Accession | NP_005861.2 |
| KEGG | hsa:10284 |
| String | 9606.ENSP00000481842 |
| Molecular Weight | Calculated MW: 18 kDa Observed MW: 18 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |