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S-Phase Kinase Associated Protein 1 (SKP1) Antibody
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Catalogue No: abx030980
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.
Research Articles on S-Phase Kinase Associated Protein 1 (SKP1)
| Target | S-Phase Kinase Associated Protein 1 (SKP1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 58-87 amino acids from the Central region of human SKP1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P63208 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DQ97, D3DQ98, P34991, Q8TAY2 |
| UniProt Entry Name | SKP1_HUMAN |
| KEGG | hsa:6500 |
| String | 9606.ENSP00000231487 |
| Molecular Weight | Calculated MW: 18.7 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Cow, Chicken, Monkey and Xenopus SKP1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |