Breast Cancer-Specific Gene 1 Protein (SNCG) Antibody

SNCG (also designated gamma synuclein or breast cancer-specific protein 1),with 127-amino acid protein (about 14kDa), belongs to the synuclein family, which also includes alpha and beta synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals,while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Target	Breast Cancer-Specific Gene 1 Protein (SNCG)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of SNCG expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O76070 (UniProt, ExPASy)
UniProt Secondary AC	O15104, Q96P61
UniProt Entry Name	SYUG_HUMAN
Gene Symbol	SNCG
GeneID	6623
OMIM	602998
HGNC	11141
KEGG	hsa:6623
Ensembl	ENSG00000173267
String	9606.ENSP00000361087
Molecular Weight	13 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Research Articles on Breast Cancer-Specific Gene 1 Protein (SNCG)

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