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Transcription Factor SOX-2 (SOX2) Antibody
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Catalogue No: abx025415
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).
Research Articles on Transcription Factor SOX-2 (SOX2)
| Target | Transcription Factor SOX-2 (SOX2) |
| Clonality | Monoclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Mouse |
| Recommended dilutions | WB: 1/4000, IHC-P: 1/50 - 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Human SOX2 recombinant protein |
| Epitope Region | SOX2 recombinant protein |
| Isotype | IgG1 |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P48431 (UniProt, ExPASy) |
| UniProt Secondary AC | Q14537 |
| UniProt Entry Name | SOX2_HUMAN |
| NCBI Accession | NP_003097.1 |
| KEGG | hsa:6657 |
| String | 9606.ENSP00000323588 |
| Molecular Weight | Calculated MW: 34.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |