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Angiopoietin-1 Receptor / TIE2 (TEK) Antibody
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Catalogue No: abx005452
Price:
US$217.50
(Size: 20 µl)
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TEK Antibody is a Rabbit Polyclonal antibody against TEK. This gene encodes a receptor that belongs to the protein tyrosine kinase TEK family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
Research Articles on Angiopoietin-1 Receptor / TIE2 (TEK)
| Target | Angiopoietin-1 Receptor / TIE2 (TEK) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human TEK. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q02763 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K6W0, B4DH20, B4DHD3, D3DRK5, E7EWI2, Q5TCU2, Q8IV34 |
| UniProt Entry Name | TIE2_HUMAN |
| Gene Symbol | TEK |
| GeneID | 7010 |
| NCBI Accession | NP_000450.2 |
| KEGG | hsa:7010 |
| String | 9606.ENSP00000369375 |
| Molecular Weight | Calculated MW: 126 kDa Observed MW: 126 kDa |
| Buffer | PBS, pH 7.3, containing 0.09% sodium azide, 50% glycerol. |
| Concentration | > 0.2 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |