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Thy-1 Membrane Glycoprotein (THY1) Antibody
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Catalogue No: abx117215
Price:
US$522.00
(Size: 100 µl)
Orders to United States ship from United States
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THY1 Antibody is a Rabbit Polyclonal antibody against THY1. THY1 is a GPI-anchored, developmentally regulated protein involved in various signaling cascades that mediate neurite outgrowth, T cell activation, tumor suppression, apoptosis, and fibrosisIt is highly expressed on the surface of adult neurons and is thought to play a role in modulating adhesive and migRatory events, such as neurite extensionDecreased THY1 expression is associated with the development of epithelial ovarian cancer, revealing its role as a putative tumor suppressor gene of human ovarian cancerTHY1 knockout mice have impaired cutaneous immune responses and abnormal retinal developmentTHY1 is epigenetically regulated, or deregulated in some disease states, such as pulmonary fibrosisThe potentially reversible hypermethylation of the THY1 promoter offers the possibility of novel therapeutic options in this disease.
Research Articles on Thy-1 Membrane Glycoprotein (THY1)
| Target | Thy-1 Membrane Glycoprotein (THY1) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | ELISA, WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P04216 (UniProt, ExPASy) |
| UniProt Secondary AC | Q16008, Q9NSP1 |
| UniProt Entry Name | THY1_HUMAN |
| Gene Symbol | THY1 |
| GeneID | 7070 |
| KEGG | hsa:7070 |
| String | 9606.ENSP00000284240 |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |