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Human Thyrotropin Receptor (TSHR) Protein
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Catalogue No: abx060230
Price:
US$493.00
(Size: 100 µg)
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Human Thyrotropin Receptor (TSHR) Protein is a recombinant fragment of Human TSHR protein (22-260 AA), containing a His tag. Thyrotropin Receptor (TSHR), also known as Thyroid stimulating hormone receptor, is a member of the leucine-rich repeat-containing G protein-coupled receptors. G protein-coupled receptors (GPCRs) are the largest family of plasma membrane receptors. They mediate the effects of several endogenous cues and are important pharmacological targets. TSHR is primarily found on the surface of the thyroid epithelial cells. Both TSHR and its ligand TSH have evolved to acquire specificity, minimize cross-reaction to other glycoprotein hormone receptors, and modulate cognate interaction (and thereby thyrotropic activity).
Research Articles on Thyrotropin Receptor (TSHR)
| Target | Thyrotropin Receptor (TSHR) |
| Research Area | Endocrinology |
| Origin | Human |
| Expression | Recombinant |
| Tested Applications | ELISA, SDS-PAGE |
| Host | E. coli |
| Recommended dilutions | Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Form | Lyophilized |
| Purity | > 95% (SDS-PAGE) |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P16473 (UniProt, ExPASy) |
| UniProt Entry Name | TSHR_HUMAN |
| GeneID | 7253 |
| OMIM | 603372 |
| KEGG | hsa:7253 |
| String | 9606.ENSP00000441235 |
| Molecular Weight | 26 kDa |
| Sequence Fragment | 22-260 AA. |
| Tag | His tag |
| Buffer | Prior to lyophilization: 10 mM PBS, pH 7.4, containing 10% glycerol and 0.01% Proclin-300. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |