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Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B) Antibody
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Catalogue No: abx032815
Price:
US$326.25
(Size: 80 µl)
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ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.
Research Articles on Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B)
| Target | Zinc Finger And BTB Domain-Containing Protein 7B (ZBTB7B) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 440-469 amino acids from the C-terminal region of human ZBTB7B. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | O15156 (UniProt, ExPASy) |
| UniProt Secondary AC | B4E3K5, D3DV83, J3KQQ3, Q68DR2, Q96EP2 |
| UniProt Entry Name | ZBT7B_HUMAN |
| Gene Symbol | ZBTB7B |
| NCBI Accession | NP_001239335.1 NP_001243384.1 |
| KEGG | hsa:51043 |
| String | 9606.ENSP00000406286 |
| Molecular Weight | Calculated MW: 58 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |