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ATP Binding Cassette Transporter C5 (ABCC5) Antibody

Catalogue No: abx002191
Price: £120.00
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ATP Binding Cassette Transporter C5 (ABCC5) Antibody

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ABCC5 Antibody is a Rabbit Polyclonal antibody against ABCC5. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine.

Target ATP Binding Cassette Transporter C5 (ABCC5)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/1000 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human ABCC5.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O15440 (UniProt, ExPASy)
UniProt Entry Name MRP5_HUMAN
Gene Symbol ABCC5
GeneID 10057
KEGG hsa:10057
String 9606.ENSP00000333926
Molecular Weight Calculated MW: 23 kDa, 25 kDa, 155 kDa, 160 kDa
Observed MW: 185 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ATP Binding Cassette Transporter C5 (ABCC5) Antibody

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