(Size: 20 µl)
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ABCG8 Antibody is a Rabbit Polyclonal antibody against ABCG8. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
Research Articles on ATP Binding Cassette Subfamily G Member 8 (ABCG8)
||ATP Binding Cassette Subfamily G Member 8 (ABCG8)
||WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
||Recombinant protein of human ABCG8.
||Purified by affinity chromatography.
||Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
|UniProt Primary AC
|UniProt Secondary AC
|UniProt Entry Name
||Calculated MW: 75 kDa
Observed MW: 76 kDa
||PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
||> 0.5 mg/ml
||Shipped within 5-10 working days.
||This product is for research use only.