ABL1 (pY204) Antibody

Catalogue No: abx000093
Price: US$232.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

ABL1 (pY204) Antibody
ABL1 (pY204) Antibody ABL1 (pY204) Antibody

Available Options

* Size:

ABL1 (pY204) Antibody is a Rabbit Polyclonal antibody against ABL1 (pY204). The ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of c-Abl protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain turns ABL1 into an oncogene. The t(9;22) translocation results in the head-to-tail fusion of the BCR (MIM:151410) and ABL1 genes present in many cases of chronic myelogeneous leukemia. The DNA-binding activity of the ubiquitously expressed ABL1 tyrosine kinase is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function for ABL1. The ABL1 gene is expressed as either a 6- or 7-kb mRNA transcript, with alternatively spliced first exons spliced to the common exons 2-11.

Target ABL1 (pY204)
Reactivity Human, Mouse
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IF/ICC
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y204 of human ABL1.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 122 kDa/124 kDa
Observed MW: Refer to Figures
Swiss Prot P00519
GeneID 25
Gene Symbol ABL1
OMIM 189980
Ensembl ENSG00000097007
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

Write a review

Your Name
Your Review
Note: HTML is not translated!

Rating Bad Good

(Click to show)