Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) Antibody
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Catalogue No: abx028035
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US$326.25
(Size: 80 µl)
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Datasheet SDS
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Research Articles on Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4)
| Target | Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) |
| Research Area | Enzymes and Kinases |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ACSL4. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Storage | Aliquot and store at 2-8°C for up to 2 weeks, or at -20°C for long term storage. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | O60488 (UniProt, ExPASy) |
| UniProt Secondary AC | D3DUY2, O60848, O60849, Q5JWV8 |
| UniProt Entry Name | ACSL4_HUMAN |
| Gene Symbol | ACSL4 |
| KEGG | hsa:2182 |
| String | 9606.ENSP00000339787 |
| Molecular Weight | Calculated MW: 79.2 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse and Rat ACSL4. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |