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Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody

Catalogue No: abx001175
Price: £120.00
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ACSL5 Antibody is a Rabbit Polyclonal antibody against ACSL5. Acyl-CoA synthetase 5, a member of the ACSL gene family that catalyzes the activation of long-chain fatty acids for lipid biosynthesis, is the only ACSL isoform that is both, located on mitochondria and functionally involved in enterocyte apoptosis.ACSL5 could play a role in promoting fatty acid-induced lipoapoptosis in hepatocytes as important mechanism in fatty liver-related disorders(PMID:20470896). ACSL5 is most abundant in liver, brown adipose tissue, and intestine and is located on both the mitochondrial membrane and endoplasmic reticulum(PMID:20798351). It has 3 isoforms produced by alternative splicing. This antibody is specific to ACSL5.

Target Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ACSL5.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q9ULC5 (UniProt, ExPASy)
UniProt Secondary AC A6GV77, D3DRB3, Q6UX44, Q9UIU4
UniProt Entry Name ACSL5_HUMAN
Gene Symbol ACSL5
GeneID 51703
String 9606.ENSP00000348429
Molecular Weight Calculated MW: 73 kDa, 75 kDa, 82 kDa
Observed MW: 76 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Acyl-CoA Synthetase Long-Chain Family Member 5 (ACSL5) Antibody

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