Actin Alpha 1, Cardiac Muscle (ACTC1) Antibody

ACTC1 Antibody is a Rabbit Polyclonal antibody against ACTC1. Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Target	Actin Alpha 1, Cardiac Muscle (ACTC1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACTC1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P68032 (UniProt, ExPASy)
UniProt Secondary AC	P04270
UniProt Entry Name	ACTC_HUMAN
Gene Symbol	ACTC1
GeneID	70
NCBI Accession	NP_005150.1
KEGG	hsa:70
String	9606.ENSP00000290378
Molecular Weight	Calculated MW: 42 kDa Observed MW: 42 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Actin Alpha 1, Cardiac Muscle (ACTC1)

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