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Actinin Alpha 2 (ACTN2) Antibody

Catalogue No: abx002676
Price: £120.00
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Actinin Alpha 2 (ACTN2) Antibody

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ACTN2 Antibody is a Rabbit Polyclonal antibody against ACTN2. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

Target ACTN2
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ACTN2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35609 (UniProt, ExPASy)
UniProt Secondary AC B1ANE4, B2RCS5, Q86TF4, Q86TI8
UniProt Entry Name ACTN2_HUMAN
Gene Symbol ACTN2
GeneID 88
KEGG hsa:88
String 9606.ENSP00000443495
Molecular Weight Calculated MW: 103 kDa
Observed MW: 115 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Actinin Alpha 2 (ACTN2) Antibody

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