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Actinin Alpha 2 (ACTN2) Antibody
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Catalogue No: abx002676
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US$348.00
(Size: 60 µl)
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Datasheet SDS
ACTN2 Antibody is a Rabbit Polyclonal antibody against ACTN2. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.
Research Articles on Actinin Alpha 2 (ACTN2)
| Target | Actinin Alpha 2 (ACTN2) |
| Research Area | Developmental Science |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IF/ICC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ACTN2 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P35609 (UniProt, ExPASy) |
| UniProt Secondary AC | B1ANE4, B2RCS5, Q86TF4, Q86TI8 |
| UniProt Entry Name | ACTN2_HUMAN |
| Gene Symbol | ACTN2 |
| GeneID | 88 |
| NCBI Accession | NP_001094.1 |
| KEGG | hsa:88 |
| String | 9606.ENSP00000443495 |
| Molecular Weight | Calculated MW: 103 kDa Observed MW: 104 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
