Activin A Receptor Type 1C (ACVR1C) Antibody

REQUEST MORE INFO
Catalogue No: abx000813
Price: US$217.50
(Size: 20 µl)

Orders to United States ship from United States

Activin A Receptor Type 1C (ACVR1C) Antibody Activin A Receptor Type 1C (ACVR1C) Antibody Activin A Receptor Type 1C (ACVR1C) Antibody Activin A Receptor Type 1C (ACVR1C) Antibody Activin A Receptor Type 1C (ACVR1C) Antibody

Click on the image to see the image legend

Available Options

* Size:



Add to Shopping Cart Buy It Now GET A QUOTE

Documents

Datasheet SDS
ACVR1C Antibody is a Rabbit Polyclonal antibody against ACVR1C. ACTR-IC (Activin receptor type 1C), also referred to as Activin receptor-like kinase 7 (ALK-7), is a type I serine/threonine kinase receptor. ACTA-IC contains an extracellular binding domain, an intracellular serine/threonine kinase domain preceded by a GS box and a transmembrane domain. It is expressed throughout the digestive and central nervous system and localizes to the cell surface. Four ACTR-IC transcripts are generated by alternative splicing. Transcript 1 is the functional full length receptor, transcript 2 lacks a complete receptor binding domain and transcripts 3 and 4 are soluble proteins that lack a transmembrane domain. ACTR-IC is a receptor for Activin AB, Activin B and Nodal. In pancreatic cells, ACTR-IC forms a complex with Activin receptor type IIB (ACTR-IIB). The kinase domain of ACTR-IC can induce Smad2 and Smad3 signalling pathways. In some cell lines, ACTR-IC overexpression induces apoptosis and inhibits proliferation.

Target Activin A Receptor Type 1C (ACVR1C)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions ELISA: 1 µg/ml, WB: 1/500 - 1/1000, IHC-P: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein corresponding to ACVR1C. The exact sequence is proprietary.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q8NER5 (UniProt, ExPASy)
UniProt Secondary AC Q4ZFZ8, Q86UL1, Q86UL2, Q8TBG2
UniProt Entry Name ACV1C_HUMAN
Gene Symbol ACVR1C
GeneID 130399
NCBI Accession NP_660302.2
KEGG hsa:130399
String 9606.ENSP00000243349
Molecular Weight Calculated MW: 55 kDa
Observed MW: 55 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.
Research Articles on Activin A Receptor Type 1C (ACVR1C)


Write a review