Activin A Receptor Type 2A (ACVR2A) Antibody

ACVR2A Antibody is a Rabbit Polyclonal antibody against ACVR2A. This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene.

Target	Activin A Receptor Type 2A (ACVR2A)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/100 - 1/500, IHC-P: 1/100 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 20-140 of human ACVR2A.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P27037 (UniProt, ExPASy)
UniProt Secondary AC	B2RAB8, B4DWQ2, D3DP85, Q53TH4, Q6NWV2, Q92474
UniProt Entry Name	AVR2A_HUMAN
Gene Symbol	ACVR2A
GeneID	92
NCBI Accession	NP_001607.1
KEGG	hsa:92
String	9606.ENSP00000241416
Molecular Weight	Calculated MW: 58 kDa Observed MW: 58 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	1.81 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Activin A Receptor Type 2A (ACVR2A)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue