Adenosine Deaminase (ADA) Antibody

ADA Antibody is a Rabbit Polyclonal antibody against ADA. This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID), in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins, whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia. [provided by RefSeq, Jul 2008].

Target	Adenosine Deaminase (ADA)
Clonality	Polyclonal
Reactivity	Human, Rat
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-363 of human Adenosine Deaminase (ADA).
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P00813 (UniProt, ExPASy)
UniProt Secondary AC	Q53F92, Q6LA59
UniProt Entry Name	ADA_HUMAN
GeneID	100
NCBI Accession	NP_000013.2
KEGG	hsa:100
String	9606.ENSP00000361965
Molecular Weight	Calculated MW: 41 kDa Observed MW: 41 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Adenosine Deaminase (ADA)

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