Adrenergic Receptor Beta Kinase 1 (ADRBK1) Antibody
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Catalogue No: abx001397
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US$377.00
(Size: 60 µl)
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Datasheet SDS
ADRBK1 Antibody is a Rabbit Polyclonal antibody against ADRBK1. The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
Research Articles on Adrenergic Receptor Beta Kinase 1 (ADRBK1)
| Target | Adrenergic Receptor Beta Kinase 1 (ADRBK1) |
| Research Area | Endocrinology |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat |
| Tested Applications | WB, IHC |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant fusion protein corresponding to human ADRBK1 |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Shelf Life | 12 months. |
| UniProt Primary AC | P25098 (UniProt, ExPASy) |
| UniProt Secondary AC | B0ZBE1, Q13837, Q6GTT3 |
| UniProt Entry Name | ARBK1_HUMAN |
| Gene Symbol | GRK2 |
| GeneID | 156 |
| NCBI Accession | NP_001610.2 |
| KEGG | hsa:156 |
| String | 9606.ENSP00000312262 |
| Molecular Weight | Calculated MW: 79 kDa Observed MW: 80 kDa |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Concentration | 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
